Residues in drinking water were based on modelling data. Acephate is considered toxic to bees with an LC 50 of 1.2 μg per bee. The PMRA will assess the combined risks of organophosphate pesticides once all individual organophosphates have been re-evaluated. Acephate is an organophosphate insecticide used on a variety of crops, including lettuce, celery, peppers, cotton, and beans. When assessing health risks, two key factors are considered: The dose levels used to assess risks are established to protect the most sensitive human population (for example, children and nursing mothers). To obtain a full copy of Proposed Re-evaluation Decision PRVD2019-04, Acephate and Its Associated End-use Products please contact our publications office. Crops with minor use registrations identified as having particular value are the following: aphids on celery; blackheaded fireworm on cranberry; and the pipette and syringe application method to trees for the control of sucking and chewing insects. The proposed regulatory decision pertaining to human health was presented in PRVD2016-01, which included, among other mitigation measures, a prohibition of foliar application in residential areas, the cancellation of uses on potatoes, and the replacement of the soluble powder formulation with a pellet formulation. A pellet formulation was determined to be an acceptable alternative to the soluble powder formulation for most uses, which would require registration for the pellet formulation. Proposed REIs range from 12 hours to 20 days. For more details on the information presented in this Summary, please refer to the Science Evaluation of Proposed Re-evaluation Decision PRVD2016-01, Acephate. Acephate contributes to pest management in the ornamental industry. During the comment period for PACR2004-40, the registrant indicated that a pellet formulation would be an alternative to a closed system for the soluble powder formulation. MRLs are specified for acephate and methamidophos on a wide range of commodities. Subsequently, the technical registrants of methamidophos voluntarily discontinued all methamidophos products and the registrations expired in 2012. In the absence of data to estimate risk, a label direction specifying “Not for use with fogging equipment” is required. For uses where changes to the use pattern are proposed as mitigation measures, Health Canada is asking stakeholders to comment on the agronomic feasibility of the proposed changes and the potential impact on the associated pest management practices. An ARI of 1 or greater indicates that exposure to both compounds is not of concern. The mitigation measures considered included the removal of acephate use on potatoes, the reduction of application rates and number of applications per season, as well as increasing minimum application intervals for several crop uses. What is the proposed Re-evaluation Decision? Other labelled uses of acephate are proposed for continued registration with mitigation measures to protect human health and/or the environment. 610-491-2800 There are no additional data required under section 12 of the Pest Control Products Act. As a result, a risk assessment for the pellet formulation was also conducted for all foliar, soil injection and some tree injection application scenarios currently registered on the label of the soluble powder product. Although the postapplication risk assessment for the horticultural scenarios identified risks of concern based on the current use pattern, the risk estimates include a number of uncertainties. Acephate and its major transformation product, methamidophos, break down quickly in soil and water and are not expected to persist in the environment. Acephate 97UP contains a water-soluble systemic insecticide which helps to reduce injury to cotton seedlings by several insects. Most proposed REIs are agronomically feasible. Proposed protective measures to reduce worker exposure require consultation with user groups to determine their acceptability. When using the pellet formulation with the various application equipment, the calculated MOEs meet the target MOE with minimal mitigation, such as baseline PPE for most crops and a respirator for a few specific uses. In addition, for some uses of acephate, there are limited alternative active ingredients, or few other pest management options for the purpose of managing insecticide resistance. 630 Freedom Business Center, Suite 402. Changes to label statements, including precautionary statements and buffer zones for nontarget aquatic habitats are required as a result of the environmental risk assessment. INTRODUCTION: Acephate is an organophosphate foliar spray insecticide of moderate persistence with residual systemic activity of about 10-15 days at the recommended use rate. No mitigation is required. The transformation product methamidophos was included in the risk assessment as it can be more toxic to nontarget organisms than acephate. Most uses of acephate have value in the food and non-food agriculture industry and are not of concern to human health or the environment when used according to revised label directions. No data was available to assess handler exposure from hand-held mist blowers for mist application in greenhouses. This label direction can be removed if data are submitted to estimate exposure and demonstrate no risks of concern. Used as a contact and systemic insecticide. Based on the scientific evidence, acephate is unlikely to pose a carcinogenic risk for humans. on roses and greenhouse ornamentals). Some naturally occurring insect biotypes resistant to TITAN Acephate 970 SG Insecticide and other Group 1B insecticides may exist through normal genetic variability in any insect population. 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