Application of GC-triple quadrupole MS in the quantitative confirmation of polycyclic aromatic hydrocarbons and phthalic acid esters in soil. Phthalic acid esters have been used as plasticizers in numerous products and classified as endocrine-disrupting compounds. Uses Phthalate esters plasticizers. Source; PubMed; Authors: Ivana Bajkin. Phthalic acid is the final common metabolite of phthalic acid esters (PAEs). Recent studies show that DEP, a phthalic acid ester (PAE), is enzymatically hydrolyzed to its monoesters by pancreatic cholesterol esterase (CEase) in pigs and cows. Epub 2019 Oct 14. … See all Hide authors and affiliations. However, their effect on antibody concentrations in children is still under investigation. Some of the PAEs are also used as the vehicle for perfumes. A wide variety of phthalic acid ester options are available to you, such as grade standard, usage, and type. Epub 2019 Oct 13. Phthalic acid esters (PAEs) have long been known as the most widely used plasticizer with a broad range of industrial application. Cyclic organosilicon esters of ortho-phthalic acids, Chemistry of Heterocyclic Compounds, 10.1007/s10593-019-02592-5, (2019). Article; Info & Metrics; eLetters; PDF; This is a PDF-only article. Chronic toxicity and carcinogenicity studies of several phthalic acid esters (PAEs) and compounds containing a 2-ethylhexyl moiety were conducted in Fischer 344 rats and B6C3F1 (hybrid) mice. Related Catalog Phthalic anhydride can also be prepared from phthalic acid by simple thermal dehydration. 46-47 DOI: 10.1126/science.178.4056.46 . Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA). PAEs are ubiquitous in different environments and our daily life due to their large and widespread application. Phthalic Acid Ester. Phthalic acid esters (PAEs) are the most commonly used plasticizers which are added to provide desired flexibility and clarity to the polyvinyl chloride (PVC) plastics used in packaging, storage and delivery of food, drugs and cosmetics. Urban sprawl worldwide warrants the use of large quantities of industrial and household products containing phthalic acid esters (PAEs) resulting in adverse impacts on the quality of aquatic life in urban watercourses. The dramatic increase in the production of synthetic fibers, processed foods, pesticides, plastics, pharmaceuticals, and a thousand other materials has completely altered our immediate human environment and provided a wealth of new materials. Science 06 Oct 1972: Vol. It has been reported that exposure to PAE affects the immune response. Phthalic acid diethyl ester 99%; EC Number: 201-550-6; find Sigma-Aldrich-P5787 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. Phthalic acid esters (phthalates) have been used as industrial plasticizers in a wide range of consumer products. Phthalic Acid Esters: Biological ImpactUncertain Phthalic acid esters-approximately 1 billion pounds in 1972-are widely used in industry, in the home, and in medical sciences. Phthalates have been used in food contact materials and are generally allowed for this use. Phthalates are also ubiquitous food an … Di-(2-ethylhexyl) phthalate was the major phthalic acid ester in the Mississippi River estuary, with mean levels of 0.1 μg/g (dry weight) in surface sediments, 1.0 μg/liter in river water, and 0.7 μg/liter in delta water. 44.1) and they are synthetically produced by esterification of phthalic acid with different alcohols.Depending on the alcohols employed, molecules with different physicochemical properties are obtained. The average concentrations of ΣPAEs in water samples were 3.16 ± 2.16 μg L -1 in … . Polyethylene terephthalate (PET) and glass are both widely used materials for bottled drinking water. Author information: (1)Sichuan Environmental Monitoring Centre, Chengdu, Sichuan, 610041, P.R. Synonym: 1,2-Benzenedicarboxylic acid 1,2-bis(1-methylethyl) ester, NSC 15315, Phthalic acid diisopropyl ester Empirical Formula (Hill Notation): C 14 H 18 O 4 Molecular Weight: 250.29 Phthalic Acid Esters: Biological Impact Uncertain. Liao C(1), Yang P, Xie Z, Zhao Y, Cheng X, Zhang Y, Ren Z, Guo Z, Liao J. Phthalates are also ubiquitous food and environmental contaminants. May 2014; Medicinski Pregled 67(5-6):172-5; DOI: 10.2298/MPNS1406172B. Monitoring took place in twelve regions of the Czech Republic. Phthalic acid esters (PAE) are widely used during chemical synthesis and do not form covalent linkages with products. Phthalic Acid Phthalate Ester Bioaccumulation Factor Phthalic Anhydride High Performance Liquid Chromatogra These keywords were added by machine and not by the authors. 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